Nail delivery has interest for local treatment of nail diseases. Nevertheless, the low\npermeability of drugs in the nail plaque precludes the efficacy of local treatments. The use of\npenetration enhancers can increase drug permeability and improve the efficacy of the treatment of nail\npathologies. In this work, different chemical substances have been evaluated as potential penetration\nenhancers. With this aim, the effect of different substances such as sodium lauryl sulfate (SLS),\npolyethylene glycol 300 (PEG 300), carbocysteine, N-acetylcysteine, lactic acid, potassium phosphate,........
Loading....